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pentobarbital will boost the degree or outcome of ivosidenib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of ivosidenib with sturdy CYP3A4 inducers lessened ivosidenib plasma concentrations.pentobarbital will lessen the extent or impact of conjugated estrogens, vaginal by impacting